Ubiquitously expressed nuclear protein; Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication- independent chromatin assembly; Belongs to the ubinuclein family.
Synonyms: UBN1, UBN1p, hUBN1, K7EQR1, K7ER78 ...