COMPARTMENTS

Subcellular localization database

UBN1 localizations

UBN1 [ENSP00000379894]

Ubiquitously expressed nuclear protein; Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication- independent chromatin assembly; Belongs to the ubinuclein family.

Synonyms:  UBN1,  UBN1p,  hUBN1,  K7EQR1,  K7ER78 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence