COMPARTMENTS

Subcellular localization database

RAPGEF4 localizations

RAPGEF4 [ENSP00000380271]

cAMP-regulated guanine nucleotide exchange factor II; Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2 (By similarity).

Synonyms:  RAPGEF4,  RAPGEF4p,  hRAPGEF4,  B7Z278,  CGEF2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence