COMPARTMENTS

Subcellular localization database

MEX3C localizations

MEX3C [ENSP00000385610]

RING finger and KH domain-containing protein 2; E3 ubiquitin ligase responsible for the post- transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation; Ring finger proteins

Synonyms:  MEX3C,  MEX3Cp,  hMEX3C,  B2R538,  B3KTW5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence