Subcellular localization database

SOS1 localizations

SOS1 [ENSP00000387784]

Son of sevenless homolog 1 (Drosophila); Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity); Pleckstrin homology domain containing

Synonyms:  SOS1,  SOS1p,  hSOS1,  C9K0N6,  G5E9C8 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence