Subcellular localization database

TNRC6B localizations

TNRC6B [ENSP00000401946]

Trinucleotide repeat-containing gene 6B protein; Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes; Armadillo-like helical domain containing

Synonyms:  TNRC6B,  TNRC6Bp,  hTNRC6B,  A0A024R1N5,  A0A024R1T4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence