COMPARTMENTS

Subcellular localization database

CACTIN localizations

CACTIN [ENSP00000415078]

Cactin, spliceosome C complex subunit; Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing; Belongs to the CACTIN family.

Synonyms:  CACTIN,  CACTIN-001,  CACTIN-002,  CACTIN-003,  CACTIN-004 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence