Cactin, spliceosome C complex subunit; Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing; Belongs to the CACTIN family.
Synonyms: CACTIN, CACTIN-001, CACTIN-002, CACTIN-003, CACTIN-004 ...