COMPARTMENTS

Subcellular localization database

ZCCHC8 localizations

ZCCHC8 [ENSP00000438993]

TRAMP-like complex RNA-binding factor ZCCHC8; Scaffolding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non- coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor SKIV2L2/MTR4, which links to RNA-binding protein adapters. May be involved in pre-mRNA splicing (Probable).

Synonyms:  ZCCHC8,  ZCCHC8p,  hZCCHC8,  F5GX80,  F5GXQ6 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence