APOA5 localizations
APOA5 [ENSP00000445002]
Apolipoprotein A-V; Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin . ECO:0000269|PubMed:11588264, ECO:0000269|PubMed:12899628,
Synonyms: APOA5, APOA5p, hAPOA5, A0A0B4RUS7, C9JZZ0 ...