COMPARTMENTS

Subcellular localization database

FXYD3 localizations

FXYD3 [ENSP00000473929]

Sodium/potassium-transporting ATPase subunit FXYD3; Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes.

Synonyms:  FXYD3,  FXYD3p,  hFXYD3,  FXYD3-001,  FXYD3-002 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence