COMPARTMENTS

Subcellular localization database

CCL3 localizations

CCL3 [ENSP00000477908]

Macrophage inflammatory protein 1-alpha; Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV); Belongs to the intercrine beta (chemokine CC) family.

Synonyms:  CCL3,  CCL3p,  hCCL3,  G0S19-1,  MIP1A ...

Linkouts:  STRING  Pharos

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence