COMPARTMENTS

Subcellular localization database

SLC46A1 localizations

SLC46A1 [ENSP00000480703]

Solute carrier family 46 (folate transporter), member 1; Has been shown to act both as an intestinal proton- coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme; Solute carriers

Synonyms:  SLC46A1,  SLC46A1p,  hSLC46A1,  A0A024QZ15,  A0A024QZ44 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence