COMPARTMENTS

Subcellular localization database

TBC1D2 localizations

TBC1D2 [ENSP00000481721]

Prostate antigen recognized and identified by SEREX 1; Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.

Synonyms:  TBC1D2,  TBC1D2p,  hTBC1D2,  A0A024R166,  Q9BYX2 ...

Linkouts:  STRING  Pharos  UniProt

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence