GCKR localizations
GCKR [ENSP00000264717]
Glucokinase (hexokinase 4) regulator; Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6- phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Synonyms: GCKR, F5H1P6, GCKR-001, GCKR-002, GCKR-003 ...