L3MBTL2 localizations
L3MBTL2 [ENSP00000216237]
Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Synonyms: L3MBTL2, L3MBTL2p, hL3MBTL2, A0A0S2Z5X6, F8WBL1 ...
Linkouts: STRING Pharos UniProt OMIM
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