CHGA localizations
CHGA [ENSP00000216492]
p-Glu serpinin precursor; [Pancreastatin]: Strongly inhibits glucose induced insulin release from the pancreas. [Serpinin]: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.
Synonyms: CHGA, G3V2Q7, G5E968, P10645, G3V2Q7p ...
Linkouts: STRING Pharos UniProt OMIM
Fetching ...
Fetching ...
Fetching ...