TG localizations
TG [ENSP00000220616]
Thyroglobulin; Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) . The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen (By similarity). Following TG re- internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (By similarity).
Synonyms: TG, E5RG33, E7EVM0, H0YB42, H0YBC5 ...
Linkouts: STRING Pharos UniProt OMIM
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