ITGB8 localizations
ITGB8 [ENSP00000222573]
Integrin beta-8; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin . It recognizes the sequence R-G-D in its ligands . Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (Probable). Required during vasculogenesis (By similarity).
Synonyms: ITGB8, ITGB8p, hITGB8, P26012, P26012p ...
Linkouts: STRING Pharos UniProt OMIM
Fetching ...
Fetching ...
Fetching ...