AIMP2 localizations
AIMP2 [ENSP00000223029]
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex . Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Synonyms: AIMP2, AIMP2p, hAIMP2, A0A024QZY1, A8MU58 ...
Linkouts: STRING Pharos UniProt OMIM
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