EDF1 localizations
EDF1 [ENSP00000224073]
Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism.
Synonyms: EDF1, EDF1p, hEDF1, O60869, O60869p ...
Linkouts: STRING Pharos UniProt OMIM
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