MSX2 localizations
MSX2 [ENSP00000239243]
Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter; Belongs to the Msh homeobox family.
Synonyms: MSX2, MSX2p, hMSX2, D6RIS4, P35548 ...
Linkouts: STRING Pharos UniProt OMIM
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