PLCG1 localizations
PLCG1 [ENSP00000244007]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Synonyms: PLCG1, PLCG1p, hPLCG1, A0A0D9SEK2, M0QX77 ...
Linkouts: STRING Pharos UniProt OMIM
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