NECTIN2 localizations
NECTIN2 [ENSP00000252483]
Nectin-2; Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive . Probable cell adhesion protein ; Belongs to the nectin family.
Synonyms: NECTIN2, NECTIN2p, hNECTIN2, K7EK87, K7EKE8 ...
Linkouts: STRING Pharos UniProt OMIM
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