TFCP2 localizations
TFCP2 [ENSP00000257915]
Alpha-globin transcription factor CP2; Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. ECO:0000269|PubMed:10455131, ECO:0000269|PubMed:1732747,; Belongs to the grh/CP2 family. CP2 subfamily.
Synonyms: TFCP2, TFCP2p, hTFCP2, A0A024R120, F8VWL0 ...
Linkouts: STRING Pharos UniProt OMIM
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