CCL21 localizations
CCL21 [ENSP00000259607]
C-C motif chemokine 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Synonyms: CCL21, CCL21p, hCCL21, O00585, Q5VZ73 ...
Linkouts: STRING Pharos UniProt OMIM
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