KLKB1 localizations
KLKB1 [ENSP00000264690]
Plasma kallikrein heavy chain; The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin; Belongs to the peptidase S1 family. Plasma kallikrein subfamily.
Synonyms: KLKB1, KLKB1p, hKLKB1, C9J075, C9JCT1 ...
Linkouts: STRING Pharos UniProt OMIM
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