ERBB3 localizations
ERBB3 [ENSP00000267101]
Receptor tyrosine-protein kinase erbB-3; Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase . May also be activated by CSPG5 . Involved in the regulation of myeloid cell differentiation .
Synonyms: ERBB3, ERBB3p, hERBB3, A0A2R8Y6T4, B3KWG5 ...
Linkouts: STRING Pharos UniProt OMIM
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