SAE1 localizations
SAE1 [ENSP00000270225]
SUMO-activating enzyme subunit 1, N-terminally processed; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. ECO:0000269|PubMed:11451954, ECO:0000269|PubMed:11481243, ECO:0000269|PubMed:15660128, ECO:0000269|PubMed:20164921,
Synonyms: SAE1, SAE1p, hSAE1, A0A024R0R4, B3KNJ4 ...
Linkouts: STRING Pharos UniProt OMIM
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