SLC47A1 localizations
SLC47A1 [ENSP00000270570]
Multidrug and toxin extrusion protein 1; Solute transporter for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. ECO:0000269|PubMed:16996621, ECO:0000269|PubMed:17495125,
Synonyms: SLC47A1, SLC47A1p, hSLC47A1, E7EX57, I3L345 ...
Linkouts: STRING Pharos UniProt OMIM
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