COMPARTMENTS

WNT3A [ENSP00000284523]

Protein Wnt-3a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:20093360, PubMed:21244856, PubMed:24841207, PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) . ECO:0000269|PubMed:20093360, ECO:0000269|PubMed:21244856,

Synonyms:  WNT3A,  WNT3Ap,  hWNT3A,  P56704,  P56704p ...

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