COMPARTMENTS

DRC1 [ENSP00000288710]

Dynein regulatory complex protein 1; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules . ; Belongs to the DRC1 family.

Synonyms:  DRC1,  DRC1p,  hDRC1,  A0A3B3IT12,  F8WE02 ...

Linkouts:  STRING  Pharos  UniProt