ACOX1 localizations
ACOX1 [ENSP00000293217]
Peroxisomal acyl-CoA oxidase 1, A chain; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs . Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length . Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs . Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA .
Synonyms: ACOX1, ACOX1p, hACOX1, I3L0T4, I3L2U4 ...
Linkouts: STRING Pharos UniProt OMIM
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