CAPN2 localizations
CAPN2 [ENSP00000295006]
Calpain-2 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' . Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
Synonyms: CAPN2, CAPN2p, hCAPN2, C9JWY7, P17655 ...
Linkouts: STRING Pharos UniProt OMIM
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