COMPARTMENTS

CXCR1 [ENSP00000295683]

C-X-C chemokine receptor type 1; Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Synonyms:  CXCR1,  CXCR1p,  hCXCR1,  P25024,  P25024p ...

Linkouts:  STRING  Pharos  UniProt  OMIM