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Subcellular localization database

JensenLab
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RHO localizations

RHO [ENSP00000296271]

Rhodopsin; Photoreceptor required for image-forming vision at low light intensity . Required for photoreceptor cell viability after birth . Light- induced isomerization of the chromophore 11-cis-retinal to all-trans- retinal triggers a conformational change that activates signaling via G-proteins (PubMed:8107847, PubMed:28524165, PubMed:26200343, PubMed:28753425). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling . ECO:0000269|PubMed:26200343, ECO:0000269|PubMed:28753425, ECO:0000269|PubMed:7846071, ECO:0000269|PubMed:8107847,

Synonyms:  RHO,  P08100,  P08100p,  hP08100,  4ZWJ ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

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The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.