ICE1 localizations
ICE1 [ENSP00000296564]
Little elongation complex subunit 1; Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III . Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies . ; Belongs to the ICE1 family.
Synonyms: ICE1, ICE1p, hICE1, A0A096LPH9, Q9Y2F5 ...
Linkouts: STRING Pharos UniProt
Knowledge
| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Extracellular space | GO_Central | IBA | ★★★☆☆ |
| Cytoplasm | UniProtKB-SubCell | IEA | ★★★☆☆ |
| Plasma membrane | GO_Central | IBA | ★★★☆☆ |
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Predictions
| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Extracellular region | PSORT | 24.5/32 | ★★★☆☆ |
| Plasma membrane | YLoc | 96.8% | ★★☆☆☆ |
| Plasma membrane | PSORT | 13.5/32 | ★★☆☆☆ |
| Lysosome | PSORT | 5/32 | ★☆☆☆☆ |