COMPARTMENTS

ABCE1 [ENSP00000296577]

ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly; Belongs to the ABC transporter superfamily. ABCE family.

Synonyms:  ABCE1,  ABCE1p,  hABCE1,  D6R9I9,  D6RGF4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM