COMPARTMENTS

SHH [ENSP00000297261]

Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).

Synonyms:  SHH,  C9JC48,  F8WB84,  F8WEH4,  Q15465 ...

Linkouts:  STRING  Pharos  UniProt  OMIM