COMPARTMENTS

CLEC1B [ENSP00000298527]

C-type lectin domain family 1 member B; C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN . After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 . (Microbial infection) Acts as an attachment factor for Human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets .

Synonyms:  CLEC1B,  CLEC1Bp,  hCLEC1B,  H7BYT7,  Q9P126 ...

Linkouts:  STRING  Pharos  UniProt  OMIM