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Subcellular localization database

JensenLab
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TTLL5 localizations

TTLL5 [ENSP00000298832]

Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha-tubulin (By similarity). Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules . Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction . ; Belongs to the tubulin--tyrosine ligase family.

Synonyms:  TTLL5,  TTLL5p,  hTTLL5,  A0A087WUG0,  G3V2J9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence

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The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.