COMPARTMENTS

P2RY1 localizations

P2RY1 [ENSP00000304767]

P2Y purinoceptor 1; Receptor for extracellular adenine nucleotides such as ADP . In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation . ; Belongs to the G-protein coupled receptor 1 family.

Synonyms: P2RY1, P2RY1p, hP2RY1, P47900, P47900p ...

Linkouts: STRING Pharos UniProt OMIM

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The subcellular localizations are derived from database annotations, automatic text mining of the biomedical literature, and sequence-based predictions. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Janos Binder, Sune Frankild, Kalliopi Tsafou, Christian Stolte, Sean O'Donoghue, Reinhard Schneider, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research (CPR), the Luxembourg Centre for Systems Biomedicine (LCSB), and the Commonwealth Scientific and Industrial Research Organisation (CSIRO).

Currently maintained by Qingyao Huang at Swiss Institute of Bioinformatics, University of Zurich. Licensed under CC BY 4.0.