FBXO22 localizations
FBXO22 [ENSP00000307833]
F-box only protein 22; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome- dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.
Synonyms: FBXO22, FBXO22p, hFBXO22, H3BRE0, H3BTH6 ...
Linkouts: STRING Pharos UniProt OMIM
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