MPDZ localizations
MPDZ [ENSP00000320006]
Multiple PDZ domain protein; Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.
Synonyms: MPDZ, A0A075B6R8, B7ZB24, F5H1U9, F5H8D6 ...
Linkouts: STRING Pharos UniProt
Knowledge
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| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Synapse | UniProtKB | CURATED | ★★★★★ |
| Apical plasma membrane | UniProtKB | CURATED | ★★★★★ |
| Apicolateral plasma membrane | UniProtKB | IDA | ★★★★★ |
| Dendrite | UniProtKB | CURATED | ★★★★★ |
| Cytoplasm | UniProtKB | IDA | ★★★★★ |
| Plasma membrane | UniProtKB | CURATED | ★★★★★ |
| Bicellular tight junction | UniProtKB | CURATED | ★★★★★ |
| Postsynaptic density | UniProtKB | CURATED | ★★★★★ |
| Plasma membrane | GO_Central | IBA | ★★★☆☆ |
| Bicellular tight junction | UniProtKB-SubCell | IEA | ★★★☆☆ |
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Predictions
| Name | Source | Evidence | Confidence |
|---|---|---|---|
| Cytosol | YLoc | 100.0% | ★★★☆☆ |
| Cytosol | PSORT | 17.5/32 | ★★☆☆☆ |
| Nucleus | PSORT | 17.3/32 | ★★☆☆☆ |
| Plasma membrane | PSORT | 10/32 | ★☆☆☆☆ |