WDFY4 localizations
WDFY4 [ENSP00000320563]
WD repeat- and FYVE domain-containing protein 4; Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
Synonyms: WDFY4, WDFY4p, hWDFY4, A0A1W2PQ91, Q6ZS81 ...
Linkouts: STRING Pharos UniProt OMIM
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