NKX2-5 localizations
NKX2-5 [ENSP00000327758]
Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter . It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development. ECO:0000269|PubMed:22560297, ECO:0000269|PubMed:22849347,
Synonyms: NKX2-5, A0A0S2Z383, A0A0S2Z3K2, E5RH49, P52952 ...
Linkouts: STRING Pharos UniProt
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