IZUMO1 localizations
IZUMO1 [ENSP00000327786]
Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg . The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion . The ligand- receptor interaction probably does not act as a membrane 'fusogen' .
Synonyms: IZUMO1, IZUMO1p, hIZUMO1, M0R0B8, Q8IYV9 ...
Linkouts: STRING Pharos UniProt OMIM
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