COMPARTMENTS

P2RX7 [ENSP00000330696]

P2X purinoceptor 7; Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .

Synonyms:  P2RX7,  P2RX7p,  hP2RX7,  F5H237,  F5H2X6 ...

Linkouts:  STRING  Pharos  UniProt