COMPARTMENTS

NFAM1 [ENSP00000333680]

NFAT activation molecule 1; May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

Synonyms:  NFAM1,  NFAM1p,  hNFAM1,  F8WE95,  Q8NET5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM