SEL1L localizations
SEL1L [ENSP00000337053]
Protein sel-1 homolog 1; Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins . Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.
Synonyms: SEL1L, SEL1Lp, hSEL1L, G3V3B3, Q9UBV2 ...
Linkouts: STRING Pharos UniProt OMIM
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