LIPA localizations
LIPA [ENSP00000337354]
Lysosomal acid lipase/cholesteryl ester hydrolase; Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor- mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation; Belongs to the AB hydrolase superfamily. Lipase family.
Synonyms: LIPA, A0A0A0MT32, P38571, Q5T073, Q5T770 ...
Linkouts: STRING Pharos UniProt OMIM
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