MIOS localizations
MIOS [ENSP00000339881]
GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 .
Synonyms: MIOS, A0A024RA24, C9JAQ1, C9JTV2, C9JUE6 ...
Linkouts: STRING Pharos UniProt OMIM
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